HORSE proposes a novel human-centric, open source, green, sustainable, coordinated provisioning and protection evolutionary platform, which can inclusively yet seamlessly combine advancements in several domains, as they get added to the system (e.g., predictive threats detection, proactive business-wise threats, and breaches mitigation actions, programmable networking, semantic communications, Network Function Virtualisation (NFV), intent-based networking, AI-based techniques, cross-layer management of physical layer features, etc.).