FISHY aims at designing, developing, validating and demonstrating a coordinated framework for cyber resilience provisioning to guarantee a trusted supply chain of ICT systems, built upon distributed, dynamic, and often fundamentally insecure and heterogeneous ICT infrastructures. The platform is envisioned not only to facilitating adaptive system reconfigurations, but also reacting to and defying the effects of cyber attacks in real time of the ICT supply chain end-to-end, and in particular in the IoT domain. The FISHY proposes a comprehensive validation and demonstration strategy built upon three use cases from different sectors, including agriculture, manufacturing and transportation. The expected project outcome is a Proof-of-Concept (PoC) of the FISHY platform, along with the dissemination and ambitious exploitation strategies.