Bio-Streams aims on supporting the optimal use (and re-use) of health data (e.g. biological, demographic, epigenetic, etc.) to generate metadata/knowledge and provide new evidence, methodologies & tools for: a) creating and deploying the Bio-Streams Biobank that will act as a scientific platform for research in obesity and better diagnostic and therapeutic approaches;b) understanding the transition from metabolically healthy to unhealthy, preventing under-age obesity; c) designing better strategies to educate & empower young citizens for weight self-management; d) coordinating authorities & policymakers to develop cross-sectoral solutions for health promotion & under-age obesity prevention.